Which type of nephritis is associated with anti-GMB positive results?

Goodpasture's syndrome is characterized by the presence of anti-glomerular basement membrane (anti-GBM) antibodies, which attack the collagen in the basement membrane of glomeruli and lungs. This autoimmune condition typically results in rapidly progressive glomerulonephritis and can lead to pulmonary hemorrhage due to its effects on the alveolar capillaries in the lungs.

The detection of anti-GBM antibodies in a patient’s serum is a key diagnostic marker for Goodpasture's syndrome. This antibody specifically targets the glomerular basement membrane, leading to the characteristic symptoms and renal pathology associated with the disease.

Other conditions listed, such as lupus nephritis and poststreptococcal glomerulonephritis, do not involve anti-GBM antibodies; rather, they have distinct pathophysiological mechanisms and associated autoantibodies. Lupus nephritis, for instance, is related to a variety of autoantibodies associated with systemic lupus erythematosus, while poststreptococcal glomerulonephritis follows infections related to specific strains of streptococci and is not linked to anti-GBM antibodies. Wegener's granulomatosis (now termed granulom