Which of the following is NOT commonly an underlying cause of cirrhosis?

Enhance your knowledge with the Internal Medicine End of Rotation Exam. Challenge yourself with multiple-choice questions and detailed explanations to ensure you excel.

Cirrhosis is a condition characterized by the replacement of healthy liver tissue with scar tissue, leading to a decline in liver function. Several factors can contribute to the development of cirrhosis, including chronic liver diseases, toxic substances, and metabolic disorders.

Chronic hepatitis B is a viral infection that can lead to inflammation and long-term liver damage, making it a well-known cause of cirrhosis. Alcohol abuse is another recognized contributor, as excessive alcohol consumption can lead to alcoholic liver disease and ultimately cirrhosis. Nonalcoholic fatty liver disease (NAFLD) is increasingly common and associated with obesity and metabolic syndrome; it can progress to nonalcoholic steatohepatitis (NASH), which can also cause cirrhosis.

On the other hand, while diabetes mellitus can have an association with liver disease, particularly in the context of metabolic syndrome and fatty liver disease, it is not considered a direct cause of cirrhosis like the others mentioned. Diabetes can increase the risk of developing fatty liver disease, which in turn can lead to cirrhosis over time. However, it does not directly cause liver damage or cirrhosis in the same way chronic hepatitis B and alcohol abuse

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