Which of the following conditions is NOT a cause of anion gap acidosis?

Enhance your knowledge with the Internal Medicine End of Rotation Exam. Challenge yourself with multiple-choice questions and detailed explanations to ensure you excel.

Anion gap acidosis occurs when there is an accumulation of unmeasured anions in the serum, leading to an increase in the anion gap calculated from the concentrations of sodium, chloride, and bicarbonate. The primary contributors to anion gap acidosis are certain metabolic derangements, toxins, and certain medical conditions.

Salicylate overdose, methanol poisoning, and some severe infections can all lead to an increased anion gap due to the production of acids that consume bicarbonate. For instance, salicylate toxicity can lead to both a primary metabolic acidosis and respiratory alkalosis due to stimulation of the respiratory center, which can significantly affect bicarbonate levels and the resulting anion gap. Methanol is similarly metabolized to formic acid, contributing to an increased anion gap due to the accumulation of this unmeasured anion.

Hyperlipidemia, on the other hand, does not typically contribute to increased anion gap acidosis. It may affect laboratory values, potentially disrupting the calculation of the anion gap by altering the concentrations of measured ions; however, hyperlipidemia itself does not produce acidic metabolites that would accumulate in the bloodstream. Thus, it is not a cause of anion gap acidosis and

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