What is a clinical manifestation of Sjogren's syndrome?

A clinical manifestation of Sjögren's syndrome is dry mouth, which is also known as xerostomia. This condition arises from the autoimmune destruction of the exocrine glands, particularly the salivary and lacrimal glands. As a result, individuals with Sjögren's syndrome often experience significant dryness in the mouth due to reduced saliva production. This can lead to difficulties in swallowing, speaking, and an increased risk of dental problems due to decreased oral moisture that usually helps in neutralizing acids and flushing away food particles.

Additionally, Sjögren’s syndrome is known for secondary symptoms that affect other exocrine glands, such as dry eyes (xerophthalmia), but the hallmark initial symptom is the dryness of the mouth. The presence of dry mouth is a distinctive feature often recognized and reported by patients, making it a key clinical manifestation of this autoimmune condition.