Arterial diseases can arise from various nonatherosclerotic disorders. Which of the following is NOT one of them?

Coronary Artery Disease (CAD) is primarily a result of atherosclerosis, which is the buildup of plaque in the arterial walls leading to narrowed or blocked arteries. This condition is directly related to risk factors such as hypertension, smoking, diabetes, high cholesterol, and lifestyle choices. Atherosclerosis is a degenerative disease characterized by the formation of plaques due to accumulation of lipids and inflammatory cells, which significantly contributes to the pathophysiology of CAD.

In contrast, the other options presented are considered nonatherosclerotic disorders. Hypertension, while it can contribute to atherosclerosis, is not itself classified as a nonatherosclerotic arterial disease; it is more frequently associated with vascular damage and contributes to the development of atherosclerosis over time. Marfan Syndrome and Ehlers-Danlos Disease are genetic connective tissue disorders that can lead to complications such as arterial aneurysms or ruptures, which are not due to plaque accumulation but rather to structural weaknesses in the blood vessel walls. Therefore, they represent examples of diseases that lead to arterial complications that are not related to atherosclerosis, reinforcing the differentiation between these conditions and coronary artery disease.